Cov roj fatty acid luv luv, suav nrog butyrate thiab nws cov ntawv muab los ntawm, tau siv ua cov khoom noj khoom haus ntxiv los thim rov qab lossis txhim kho cov teebmeem tsis zoo ntawm cov khoom xyaw los ntawm cov nroj tsuag hauv cov zaub mov aquaculture, thiab muaj ntau yam kev cuam tshuam zoo rau lub cev thiab kev noj qab haus huv hauv cov tsiaj txhu thiab tsiaj txhu. Tributyrin, ib qho butyric acid derivate, tau raug soj ntsuam ua ib qho ntxiv hauv cov zaub mov ntawm cov tsiaj ua liaj ua teb, nrog cov txiaj ntsig zoo hauv ntau hom tsiaj. Hauv ntses thiab crustaceans, kev suav nrog tributyrin hauv cov zaub mov yog tsis ntev los no thiab tau kawm tsawg dua tab sis cov txiaj ntsig qhia tias nws yuav muaj txiaj ntsig zoo rau cov tsiaj hauv dej. Qhov no yog qhov tseem ceeb tshwj xeeb rau cov tsiaj noj nqaij, uas lawv cov zaub mov yuav tsum tau ua kom zoo rau kev txo cov ntsiab lus ntawm cov ntses hmoov kom txhim kho kev ruaj khov ntawm ib puag ncig thiab kev lag luam ntawm lub sector. Cov haujlwm tam sim no piav qhia txog tributyrin thiab nthuav qhia cov txiaj ntsig tseem ceeb ntawm nws siv ua qhov chaw noj zaub mov ntawm butyric acid hauv cov pub rau cov tsiaj hauv dej. Lub ntsiab lus tseem ceeb yog muab rau cov hom tsiaj txhu thiab yuav ua li cas tributyrin, ua cov khoom noj ntxiv, tuaj yeem pab txhawb rau kev ua kom zoo dua ntawm cov khoom noj hauv dej los ntawm cov nroj tsuag.
2. Glyceryl butyrate
Butyric acid muaj ib qho tsw tsis zoo thiab yooj yim rau volatilize, thiab nws nyuaj rau ncav cuag qhov kawg ntawm txoj hnyuv kom ua lub luag haujlwm tom qab raug tsiaj noj, yog li nws tsis tuaj yeem siv ncaj qha rau hauv kev tsim khoom. Glyceryl butyrate yog cov khoom rog ntawm butyric acid thiab glycerin. Butyric acid thiab glycerin raug khi los ntawm cov ntawv cog lus covalent. Lawv ruaj khov ntawm pH1-7 txog 230 ℃. Tom qab raug tsiaj noj, glyceryl butyrate tsis lwj hauv plab, tab sis lwj mus rau hauv butyric acid thiab glycerin hauv txoj hnyuv nyob rau hauv qhov kev ua ntawm pancreatic lipase, maj mam tso butyric acid. Glyceryl butyrate, ua ib qho khoom noj khoom haus ntxiv, yooj yim siv, muaj kev nyab xeeb, tsis muaj tshuaj lom, thiab muaj ib qho tsw tshwj xeeb. Nws tsis yog tsuas yog daws qhov teeb meem uas butyric acid nyuaj rau ntxiv ua kua thiab tsw phem, tab sis kuj txhim kho qhov teeb meem uas butyric acid nyuaj rau ncav cuag txoj hnyuv thaum siv ncaj qha. Nws suav hais tias yog ib qho ntawm cov khoom zoo tshaj plaws butyric acid derivatives thiab cov khoom tiv thaiv histamine.
2.1 Glyceryl Tributyrate thiab Glyceryl Monobutyrate
Tributyrinmuaj 3 lub molecule ntawm butyric acid thiab 1 lub molecule ntawm glycerol. Tributyrin maj mam tso tawm butyric acid hauv txoj hnyuv los ntawm pancreatic lipase, ib feem ntawm nws raug tso tawm hauv pem hauv ntej ntawm txoj hnyuv, thiab ib feem ntawm nws tuaj yeem mus txog tom qab ntawm txoj hnyuv los ua lub luag haujlwm; Monobutyric acid glyceride yog tsim los ntawm ib lub molecule ntawm butyric acid khi rau thawj qhov chaw ntawm glycerol (Sn-1 qhov chaw), uas muaj cov khoom hydrophilic thiab lipophilic. Nws tuaj yeem mus txog qhov kawg ntawm txoj hnyuv nrog cov kua txiv zom zaub mov. Qee lub butyric acid raug tso tawm los ntawm pancreatic lipase, thiab qee qhov raug nqus ncaj qha los ntawm cov hlwb epithelial hauv plab hnyuv. Nws raug decomposed rau hauv butyric acid thiab glycerol hauv cov hlwb mucosal hauv plab hnyuv, txhawb kev loj hlob ntawm cov plab hnyuv villi. Glyceryl butyrate muaj molecular polarity thiab nonpolarity, uas tuaj yeem nkag mus rau hauv hydrophilic lossis lipophilic cell phab ntsa membrane ntawm cov kab mob tseem ceeb, nkag mus rau hauv cov hlwb kab mob, rhuav tshem cov qauv cell, thiab tua cov kab mob phem. Monobutyric acid glyceride muaj cov tshuaj tua kab mob zoo rau cov kab mob gram-positive thiab gram-negative, thiab muaj cov tshuaj tua kab mob zoo dua.
2.2 Kev siv glyceryl butyrate hauv cov khoom siv hauv dej
Glyceryl butyrate, ua ib qho derivative ntawm butyric acid, tuaj yeem tso tawm butyric acid nyob rau hauv qhov kev ua ntawm plab hnyuv pancreatic lipase, thiab tsis muaj ntxhiab, ruaj khov, muaj kev nyab xeeb thiab tsis muaj cov khoom seem. Nws yog ib qho ntawm cov kev xaiv zoo tshaj plaws rau cov tshuaj tua kab mob thiab siv dav hauv aquaculture. Zhai Qiuling et al. tau qhia tias thaum ntxiv 100-150 mg / kg tributylglycerol ester rau hauv pub, qhov hnyav nce, qhov kev loj hlob tshwj xeeb, kev ua ub no ntawm ntau yam enzymes zom zaub mov thiab qhov siab ntawm plab hnyuv villi ua ntej thiab tom qab ntxiv 100 mg / kg tributylglycerol ester tuaj yeem nce ntxiv ntau heev; Tang Qifeng thiab lwm tus kws tshawb fawb pom tias ntxiv 1.5g / kg tributylglycerol ester rau hauv pub tuaj yeem txhim kho kev loj hlob ntawm Penaeus vannamei, thiab txo cov lej ntawm cov kab mob pathogenic vibrio hauv plab hnyuv; Jiang Yingying et al. pom tias ntxiv 1g / kg ntawm tributyl glyceride rau hauv pub tuaj yeem ua rau qhov hnyav nce ntxiv ntawm Allogynogenetic crucian carp, txo cov coefficient pub, thiab ua rau muaj kev ua haujlwm ntawm superoxide dismutase (SOD) hauv hepatopancreas; Qee qhov kev tshawb fawb qhia tau hais tias qhov ntxiv ntawm 1000 mg / kgtributyl glyceridekev noj zaub mov tuaj yeem ua rau muaj kev ua haujlwm ntawm superoxide dismutase (SOD) hauv plab hnyuv ntawm Jian carp.
Lub sijhawm tshaj tawm: Lub Ib Hlis-05-2023
