Tributyrin yog tsim los ntawm Efine lub tuam txhab bRaws li kev tshawb fawb txog cov yam ntxwv ntawm lub cev thiab kev tswj hwm kev noj qab haus huv ntawm cov txheej txheem mucosa hauv plab hnyuv ntawm ib hom khoom noj khoom haus tshiab, tuaj yeem ua kom cov khoom noj khoom haus ntawm cov tsiaj hauv plab hnyuv sai sai, txhawb kev loj hlob thiab kev loj hlob ntawm cov hnyuv mucosa, kho txhua yam kev ntxhov siab los ntawm kev puas tsuaj ntawm cov hnyuv mucosa, tiv thaiv kev noj qab haus huv ntawm txoj hnyuv, txhawb kev ua haujlwm ntawm kev zom zaub mov thiab kev nqus ntawm txoj hnyuv, Nws tuaj yeem tiv thaiv tau kab mob necrotizing enteritis thiab txhim kho kev ua tau zoo ntawm cov tsiaj txhu thiab nqaij qaib.

Mechanism ntawm kev ua haujlwm ntawm butyric acid

Feem ntau cov roj fatty acids uas cov tsiaj txhu thiab cov nqaij qaib xav tau tuaj yeem tau los ntawm cov khoom noj (zaub mov), tab sis qee cov roj fatty acids luv luv (xws li butyric acid) feem ntau tsis muaj los ntawm cov khoom noj. Cov roj fatty acids luv luv, tshwj xeeb tshaj yog butyric acid, ua lub luag haujlwm tseem ceeb hauv kev tswj hwm kev noj qab haus huv ntawm cov tsiaj txhu thiab cov nqaij qaib, suav nrog:

1.Butyric acid yog lub zog ceev ceev rau kev kho qhov raug mob ntawm cov tsiaj txhu thiab cov nqaij qaib, uas tuaj yeem lwj thiab tso tawm lub zog sai, txhawb kev loj hlob ntawm chorionic membrane, thiab txhim kho lub cev txoj haujlwm thaiv.

2.Butyric acid tuaj yeem txo cov pa oxygen hauv txoj hnyuv, tiv thaiv kev tsim cov kab mob phem uas noj cov pa oxygen, thiab txhawb kev loj hlob ntawm cov kab mob zoo xws li cov kab mob lactic acid.

3. Butyric acid tuaj yeem ua kom cov cim qhia ntawm cov hlwb tiv thaiv kab mob hauv plab hnyuv thiab txhim kho kev tiv thaiv kab mob hauv plab hnyuv.

Cov peev txheej thiab kev sib piv ntawm butyric acid hauv pub

Cov txheej txheem metabolic ntawm butyric acid hauv cov tsiaj

Kev ua tau zoo thiab cov yam ntxwv

1.Raws li lub roj tseem ceeb rau cov hlwb epithelial hauv plab hnyuv, nws tuaj yeem muab lub zog rau cov hlwb epithelial hauv plab hnyuv sai sai, txhawb kev loj hlob ntawm cov hlwb mucosal hauv plab hnyuv, koom nrog kev saib xyuas thiab kho cov hlwb mucosal hauv plab hnyuv, thiab tswj kev ncaj ncees thiab kev ua haujlwm ntawm cov hlwb mucosal hauv plab hnyuv.

2.Qhov siab ntawm cov hnyuv villus tau nce ntxiv,txo qis qhov tob ntawm lub qhov ntxa , txhim khoqhov sib piv ntawm qhov siab ntawm txoj hnyuv mus rau qhov tob ntawm lub qhov ntxa , thiabtxhim khocov qauv morphological ntawm txoj hnyuv me.

3.Txo cov pH hauv plab hnyuv, tiv thaiv kev loj hlob ntawm cov kab mob pathogenic xws li Escherichia coli, Salmonella thiab Clostridium perfringens, txhawb kev loj hlob ntawm cov kab mob zoo ntawm cov kab mob lactic acid, tswj cov kab mob hauv plab hnyuv microecological ntawm cov tsiaj txhu thiab nqaij qaib.

4.Txhawb kev tso tawm ntawm cov tshuaj tua kab mob thiab kev loj hlob ntawm cov hlwb tiv thaiv kab mob ntawm cov hnyuv plab, txhim kho kev tiv thaiv kev ntxhov siab thiab kev tiv thaiv kab mob ntawm cov tsiaj txhu thiab nqaij qaib, txo qhov tshwm sim ntawm kev mob plab hnyuv thiab lwm yam kab mob.

Daim Duab 1Cov teebmeem ntawm triglyceride thiab Coated sodium butyrate rau kev nce txhua hnub ntawm cov qaib dawb-feathered.

Cov txiaj ntsig tau qhia tias piv rau pawg tswj, qhov nce txhua hnub ntawm cov qaib dawb feathered tau nce ntxiv los ntawm kev ntxivtributyrin, thiab qhov tshwm sim zoo dua li ntawm cov pawg sodium butyrate coated

daim duab 2 Cov teebmeem ntawm triglyceride thiab coated sodium butyrate rau ntawm cov kab mob plab hnyuv ntawm cov qaib ntxhw

Cov txiaj ntsig qhia tau tias piv rau pawg tswj, ntxivTributyrin tuaj yeem txo cov naj npawb ntawm escherichia coli hauv txoj hnyuv ntawm cov qaib ntxhw, thiab ua rau cov kab mob lactic acid ntau ntxiv, thiab qhov cuam tshuam zoo dua li ntawm cov sodium butyrate coated.

Cov teebmeem ntawm triglyceride thiab sodium butyrate rau kev loj hlob thiab kev raws plab ntawm Piglet

Cov txiaj ntsig tau qhia tias, zoo ib yam li cov txiaj ntsig ntawm cov tshuaj tua kab mob, triglyceride tuaj yeem ua rau cov menyuam npua tau txais txiaj ntsig txhua hnub los ntawm 11% ~ 14%, txo qhov piv ntawm kev pub rau nqaij los ntawm 0.13 ~ 0.15, thiab txo qhov kev raws plab ntawm cov menyuam npua, uas zoo dua li pawg sodium butyrate.

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