Ntau yam tshuaj tua kab mob hauv kev tsim cov qaib tau maj mam raug txwv thoob plaws ntiaj teb vim muaj teeb meem tsis zoo xws li cov tshuaj tua kab mob seem thiab kev tsis kam tshuaj tua kab mob. Tributyrin yog lwm txoj hauv kev rau cov tshuaj tua kab mob. Cov txiaj ntsig ntawm kev tshawb fawb tam sim no qhia tau hais tias tributyrin tuaj yeem txhim kho kev loj hlob los ntawm kev hloov pauv cov ntshav biochemical indices thiab cov kab mob hauv plab ntawm cov qaib daj-feathered. Raws li peb paub, ob peb txoj kev tshawb fawb tau tshawb nrhiav cov teebmeem ntawm tributyrin rau cov kab mob hauv plab thiab nws txoj kev sib raug zoo nrog kev loj hlob hauv cov qaib. Qhov no yuav muab lub hauv paus kev tshawb fawb rau kev siv tributyrin hauv kev yug tsiaj hauv lub sijhawm tom qab tshuaj tua kab mob no.

Butyric acid yog tsim tawm hauv cov tsiaj txoj hnyuv lumen los ntawm cov kab mob fermentation ntawm cov carbohydrates tsis tau zom thiab cov protein endogenous. 90% ntawm cov butyric acid no yog metabolized los ntawm cecal epithelial cells lossis colonocytes los muab ntau yam txiaj ntsig zoo rau kev noj qab haus huv plab.

Txawm li cas los xij, cov kua qaub butyric dawb muaj ntxhiab tsw phem thiab nyuaj rau kev tswj hwm hauv kev xyaum. Tsis tas li ntawd, cov kua qaub butyric dawb tau pom tias feem ntau raug nqus rau hauv txoj hnyuv sab saud, ua rau feem ntau tsis mus txog txoj hnyuv loj, qhov twg butyric acid yuav ua nws txoj haujlwm tseem ceeb.

Yog li ntawd, cov tshuaj sodium ntsev butyrate lag luam tau tsim los kom yooj yim rau kev tuav thiab tiv thaiv kev tso tawm ntawm butyric acid hauv txoj hnyuv sab saud.

Tab sis tributyrin muaj butyric acid thiab mono-butyrin thiab nyob rau hauv txoj hnyuv sab saud, tributyrin yog hydrolzed rau hauv butyric acid thiab α-mono-butyrin tab sis nyob rau hauv lub plab tom qab, lub molecule tseem ceeb yuav yog α-monobutyrin uas muab zog ntau dua, los txhawb kev loj hlob ntawm cov leeg thiab txhawb kev loj hlob ntawm cov hlab ntsha rau kev thauj cov as-ham zoo dua.

Muaj ntau yam kab mob cuam tshuam nrog kev noj qab haus huv ntawm cov qaib xws li:

• raws plab
• mob malabsorption syndrome
• kab mob coccidiosis
• mob plab hnyuv necrotic

Qhov ntxiv ntawm tributyrin tau siv dav los tawm tsam cov kab mob plab, thiab thaum kawg txhim kho kev noj qab haus huv ntawm qaib.

Hauv cov qaib uas tso qe, nws muaj peev xwm txhim kho kev nqus calcium tshwj xeeb tshaj yog rau cov qaib uas tso qe laus dua thiab txhim kho qhov zoo ntawm lub plhaub qe.

Hauv cov menyuam npua, kev hloov pauv ntawm kev tso zis yog lub sijhawm tseem ceeb vim muaj kev ntxhov siab hnyav los ntawm kev hloov ntawm cov kua mus rau cov khoom noj khov, kev hloov pauv ib puag ncig, thiab kev sib xyaw nrog cov phooj ywg tshiab.

Hauv kev sim menyuam npua tsis ntev los no uas peb tau ua hauv Rivalea, nws tau pom tseeb tias kev ntxiv 2.5 kg Tributyrin /MT tom qab weaning cov zaub mov rau 35 hnub tau txhim kho qhov hnyav nce 5% thiab qhov piv ntawm kev hloov pauv pub mis los ntawm 3 cov ntsiab lus.

Tributyrin kuj tseem siv tau rau hauv mis nyuj ua ib qho hloov pauv rau mis nyuj tag nrho thiab ib feem tsis lees paub qhov tsis zoo uas cov mis hloov pauv muaj rau kev loj hlob ntawm rumen.