1. Physicochemical Properties
Benzoic acid(benzenecarboxylic acid) yog qhov yooj yim tshaj plaws aromatic acid nrog qaug zog acidity (dissociation tas li 4.20). Nws yog me ntsis soluble hauv dej tab sis yooj yim soluble hauv cov kuab tshuaj organic xws li ethanol. Vim nws cov lipophilicity muaj zog, nws tuaj yeem nkag mus rau microbial cell daim nyias nyias thiab siv cov tshuaj tua kab mob los ntawm inhibiting amino acid uptake, cuam tshuam kev ua pa enzyme, thiab tiv thaiv acetyl-CoA condensation tshua.

2.Antimicrobial Spectrum: Siv tau zoo tiv thaiv kab mob, pwm, thiab cov poov xab, nrog rau kev txhim kho tshwj xeeb ntawm cov tshuaj tiv thaiv nyob rau hauv ib puag ncig acidic (xws li, thaum hloov mus rau benzoate ntsev).

3.Metabolism thiab kev nyab xeeb

Hauv cov tsiaj, benzoic acid feem ntau yog metabolized hauv daim siab, nrog ntau dua 85% tawm hauv cov zis li hippuric acid, tawm hauv qhov tsis muaj qhov seem thiab ua rau tsis muaj kev cuam tshuam rau cov kua qaub-puag tshuav.
Tib neeg thiab npua muaj cov txheej txheem metabolic zoo sib xws, nrog ze li kev tso tawm hauv 24 teev, qhia tias muaj kev nyab xeeb siab.

II. Cov ntawv thov tshwj xeeb hauv Pub

Kev Cai thiab Kev Siv Cov Qauv

EU: Txij xyoo 2003, benzoic acid tau tso cai ua cov kua qaub hauv npua noj ntawm 0.5% ~ 1.0%.
Tuam Tshoj: Sau raws li ob qho tib si pH regulator thiab preservative nyob rau hauv lubPub Additive Catalog (2013), tsis muaj qhov txwv tsis pub noj tab sis hais txog cov qauv zaub mov ntawm 0.2 ~ 1.0 g / kg.

Functions thiab Efficiency

Tshuaj tua kab mob Alternative: Ua raws li EU txoj cai lij choj xyoo 2006 txwv tsis pub siv tshuaj tua kab mob, benzoic acid tau los ua ib qho kev hloov pauv tseem ceeb vim nws qhov dav-spectrum antimicrobial zog, tshwj xeeb tshaj yog nyob rau hauv kev tiv thaiv tom qab weaning raws plab (PWD) thiab txhim kho piglet loj hlob.
Kev loj hlob zoo: Cov kev tshawb fawb qhia tias ntxiv 0.5% benzoic acid txhim kho kev noj zaub mov thiab qhov hnyav nce hauv cov piglets weaned.

Kev sib piv nrog lwm cov tshuaj ntxiv

Piv nrog rau cov poov tshuaj diformate, benzoic acid yog absorbed sai dua nyob rau hauv lub foregut thiab yuav tsum tau txheej technology los ua nyob rau hauv lub hindgut, whereas poov tshuaj diformate ncaj qha lub hom phiaj ntawm duodenum, muab ntau dua antimicrobial efficiency.